Osteoarthritis: Heart Disease for Joints
- Osteoarthritis (OA) is similar to many other chronic diseases in that its slowly developing for many years before the first symptoms appear.
- The development of atherosclerosis (hardening of the arteries) and OA both involve chronic inflammation, free radical damage and destruction of connective tissue.
- When chronic diseases have similar underlying causes, similar approaches to healing can help more than what might be bothering you at the moment.
- Diet and lifestyle changes can reduce chronic inflammation, and Joint Relief can also help by attacking inflammation and pain at the molecular, cellular and genetic levels to provide long-term relief.
by Dr. John Neustadt
Joint pain causes too many people to miss out on some of the greatest moments of their lives. While friends and family are enjoying themselves riding bikes, playing tennis, hiking, gardening, dancing or playing with their kids and grandkids, they’re sitting on the sidelines, unable to fully participate. And if they do, they’re often experiencing pain and discomfort, or paying for it later as their joint pain flares up.
There are nearly 100 different type of arthritis. They can create mild and annoying discomfort to severe and debilitating pain. But they all have one thing in common they reduce your quality of life. But it doesn’t have to be that way.
Of all the arthritides (yes, arthritides is the plural of arthritis), osteoarthritis (OA) is the most common. If you suffer from arthritis, you’re unfortunately in good company. It’s one of the leading causes of disability in the US and around the world. More than 60 million people in the US and 250 million people around the world have arthritis, including 80% of people over 50 years old.
Osteoarthritis (OA) is a chronic, degenerative disease of the connective tissue in joints. It usually occurs in the older age-group and is a nearly universal consequence of aging. And more and more people are struggling to deal with it. Since the 1950s and ‘60s, the number of people in the US with OA has doubled.
OA can strike at any age, Although primarily seen in the elderly, there is a 35% incidence of knee osteoarthritis as early as 30 years old. In these younger folks, it’s often diagnosed as chondromalacia patellae. But by the time you’re in your 70s, OA is nearly universal and is the most common of any disease.
Joint Destruction Long Before You Know it
OA is similar to many other chronic diseases in that its slowly developing for many years before the first symptoms appear. Heart disease, Alzheimer disease and Parkinson disease progress in the background, without anyone knowing for years.
The first symptom of a heart disease is usually a heart attack. But by the time you’re stopped in your tracks by severe pain and a crushing pressure in your chest, and before you break out in a cold sweat and start to realize you need help or your going to die, the disease process had already been progressing without you knowing it for many years.
Similarly, by the time someone finally seeks medical care for joint pain, they’ll typically already have advanced joint cartilage destruction. And this destruction had likely been there for years before finally creating pain.
Diagnosis is usually made based on clinical presentation. The chief symptoms of OA are pain and stiffness in the joints. It most often affects asymmetrical weight bearing joints and distal interphalangeal (DIP) joints. The pain usually increases after exercise.
OA is diagnosed as primary or secondary. In primary OA there is no known cause. Primary OA is sometimes referred to as “wear-and-tear osteoarthritis.” In secondary OA, as the label implies, OA is a result of other factors. These can include trauma such as a previous sports injuries, having an autoimmune disease or structural abnormalities.
One common surgical procedure that can lead to the development of osteoarthritis years later is surgery where part or all of the meniscus in the knee is removed. This surgery is called a meniscectomy (total removal of the meniscus) or hemi-meniscectomy (partial removal of the meniscus).
Although an X-ray is used to diagnose OA, X-rays and lab test don’t correlate with the disease what people are feeling. We can have patients with similar X-rays, but one may be experiencing severe joint pain while the other patient may have only mild or no discomfort.
Heart Disease for Joints
When describing the process of developing OA, I like to tell people it’s like getting heart disease in your joints. Similar to heart disease, it’s been developing for years without them knowing it. They both also involve inflammation and connective tissue destruction.
In atherosclerosis (hardening of the arteries), the lining of the arteries is damaged. With OA, connective tissue in and around joints is destroyed and inflammation is part of both disease processes. In both diseases, the inflammation, and the development of the disease is “silent.” This means it’s occurring without any outward signs or symptoms, until one day suddenly the symptoms appear.
Osteoarthritis usually affects weight-bearing joints such as the spine and knees. The OA disease process at the tissue and cellular level is associated with destruction and loss of cartilage, remodeling of bone and intermittent inflammation.
In the healthy adult joint, just like in other tissues throughout the body, there is a constant turnover of cells. Old, worn out cells are broken down and new healthy cells are produced. A mechanical or biochemical disruption of proper joint functioning and cell turnover initiates the downward spiral of chronic degeneration.
In OA, the rate of degeneration is faster than the rate of repair, the body’s healing mechanisms can’t keep up with the damage and joints start to degenerate, ultimately leading to pain, decreased range of motion and swelling around the joint in more advanced cases.
Similar Problems, Similar Solutions
So many chronic diseases have similar underlying causes, and thus similar approaches to healing. These include poor diet, not exercising, not getting enough sleep and inflammation. And these are risk factors for OA and heart disease too.
If you have OA and want to decrease the pain and inflammation and increase range of motion and pain-free activity, then try the following.
Nutrient deficiencies have been implicated in the onset and progression of OA. Eating more whole, organic fruits and vegetables is a good way to increase the body’s nutritional status. Antioxidants, minerals and other phytonutrients create the colors in fresh fruits and vegetables.
Eating a variety of colorful vegetables helps ensure you’re getting a variety of healthy nutrients to help your body thrive. This whole-foods, Mediterranean dietary pattern is anti-inflammatory. To transition into eating a whole foods diet, read my blog, 3-Steps to Eating Healthy for Life.
Daily non-traumatic exercise such as swimming can be helpful. Exercise has been shown to be an effective approach to managing of osteoarthritis. It can reduce impairment, improve function, and prevent disability in OA patients.
The amount of disease progression may decrease someone’s ability to participate in exercise. Range of motion exercises may help maintain joint mobility. Additionally, low impact stretching exercises, such as gentle yoga therapy is beneficial in many types of arthritis, including OA.
Sleep and Stress
The important of getting enough sleep (and high-quality sleep) and managing stress cannot be overstated. As in all chronic degenerative diseases, lifestyle plays a major role in its onset and progression. Adequate sleep and stress reduction are important components of preventing chronic diseases and play major roles in healing. If you’re having difficulty sleeping, read my Checklist to Beat Insomnia.
There are lots of clinical trials and basic research that evaluated the benefits of dietary supplements in people with OA. Specific nutrients have been shown to promote healthy joint function, reduce inflammation, increase range of motion and allow people to increase their pain-free activity level. Dietary supplements can be an important component of promoting healthy joints and can have other benefits throughout the body.
There are many nutrients available as dietary supplements that research shows can help people with osteoarthritis. But I couldn’t find the dose, form and combination of nutrients in existing products. And apparently neither could many NBI customers.
In a customer survey, the second most requested dietary supplement was one for joint pain. So I dug into the research and evaluated the underlying physical and molecular mechanisms that cause joint pain. I then evaluated hundreds of studies looking at natural approaches for helping the underlying causes of joint pain.
Based on this research I created Joint Relief, a dietary supplement that contains the combination and dose of nutrients shown in clinical trials to support joint health, decrease inflammation and increase range of motion and pain-free activity.
Bland JH, Cooper SM. Osteoarthritis: a review of the cell biology involved and evidence for reversibility. Management rationally related to known genesis and pathophysiology. Semin Arthritis Rheum. 1984;14(2):106-133. [Article]
CDC. Prevalence of disability and associated health conditions–United State, 1991-1992. MMWR. 1994;43(40):730-739. [Report]
Cross M, Smith E, Hoy D, et al. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014;73(7):1323-1330. [Article
Garfinkel M, Schumacher HR, Jr. Yoga. Rheum Dis Clin North Am. 2000;26(1):125-132, x. [Article]
Lawrence JS, Bremner JM, Bier F. Osteo-arthrosis. Prevalence in the population and relationship between symptoms and x-ray changes. Ann Rheum Dis. 1966;25(1):1-24. [Article]
Lohmander LS. What can we do about osteoarthritis? Arthritis Res. 2000;2(2):95 – 100. [Article]
Minor MA. Exercise in the treatment of osteoarthritis. Rheum Dis Clin North Am. 1999;25(2):397-415, viii. [Article]
Petty CA, Lubowitz JH. Does arthroscopic partial meniscectomy always cause arthritis? Sports Med Arthrosc Rev. 2012;20(2):58-61. [Article]
Sinkov V, Cymet T. Osteoarthritis: understanding the pathophysiology, genetics, and treatments. J Natl Med Assoc. 2003;95(6):475-482. [Article]
Sowers M. Epidemiology of risk factors for osteoarthritis: systemic factors. Curr Opin Rheumatol. 2001;13(5):447-451. [Article]
Wallace IJ, Worthington S, Felson DT, et al. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci U S A. 2017;114(35):9332-9336. [Article]
Article at-a-glance: Whether you’re sautéing, baking or drizzling it over vegetables, cooking oil is an indispensable part of any kitchen Our bodies need fat, which is critical for a balanced mood, optimal hormone function, and a healthy nervous and immune system. ...
The number of people with problems sleeping is epidemic. Nearly everyone has some difficulty sleeping at some point in their lives, but seventy million Americans suffer from diagnosed sleep disorders. And what we know is that if that many people have been...
Article at-a-glance: Americans are sleep deprived, and insomnia is a common problem, especially as we get older To address insomnia, we must first address our ability to handle stress The body’s innate stress response system, the hypothalamic pituitary adrenal (HPA)...